What polynucleotides do, why they calm and repair, and where they fit in a regenerative protocol.
PDRN (polydeoxyribonucleotide) is a regenerative active derived from purified DNA fragments. It works by signalling the skin to repair itself — boosting fibroblast activity, hydration and collagen while calming inflammation.
Calm, then repair
Its anti-inflammatory and antioxidant properties make PDRN especially valuable after procedures like laser, microneedling or peels, where it speeds recovery and reduces redness.
In the Préime range
Préime PDRN Booster delivers pharmaceutical-grade polynucleotides validated through clinical research — improving elasticity, hydration and tone across a wide range of protocols, and pairing beautifully with exosome therapy.
The result is skin that doesn't just look better immediately, but is genuinely healthier and more resilient over time.
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